Hyperlane is a permissionless interoperability protocol connecting over 170 chains, focusing on flexible, modular cross-chain messaging. Synapse is a universal cross-chain liquidity and communication network that emphasizes bridging assets and data across multiple ecosystems. Hyperlane suits developers seeking customizable, permissionless integrations, while Synapse is better for users and protocols needing straightforward cross-chain token swaps and generalized messaging.
| Token Price | — | — |
| 24h Change | — | — |
| Market Cap | — | — |
| TVL | $87.9MDefiLlama | $11.9MDefiLlama |
| MCap Rank | #762 | #480 |
| Total Raised | $18.5M | $2.0M |
| Founded | 2022 | 2025 |
| Stage | — | — |
| X / Twitter | 125K | 72K |
| GitHub Stars | 187 | — |
| Chains | arbitrumavalanchebase | arbitrumauroraavalanche |
| Tags | Infra, Cross-Chain Communication, Infra | Bridge, Infra, AI |
Hyperlane is an open-source, permissionless interoperability framework connecting over 170 blockchains. It enables cross-chain messaging, asset bridging, and interchain applications, evolving into a decentralized infrastructure layer for a global payment network.
Synapse is a cross-chain protocol that enables frictionless interoperability between blockchains, allowing users to bridge and swap assets, provide liquidity, and send generalized messages across L1s, sidechains, and L2s. It powers decentralized, permissionless transactions and supports new cross-chain primitives.

