
Big Brain Holdings
Venture CapitalBig Brain Holdings is a crypto-exclusive fund investing in pre-seed, seed, and early-stage projects. We believe in a crypto-forward future and invest in teams paving the way towards that future. The team focuses on projects that are unique, innovative, and on the cutting edge of blockchain. Big Brain Holdings values long-term partnerships and helps the projects we invest in grow and prosper through our various value-added benefits.
Portfolio
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Multi-chain financial product protocols

A cross-chain Lending market

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Disrupting deFi through automation

Chess Battle Royale game

The Perpetuals Exchange on MegaETH

The firm behind popular NFT projects DeGods and y00ts

The hyperscalable EVM protocol on Arweave

Hybrid Crypto Trading Platform

Cross-chain Swap Auction Protocol

A web3 puzzle game protocol

Solana developer platform

Web3 product studio

Trading-focused multi-chain L2 network

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AI infrastructure and products for digital creators

Mobile game studio

Social sandbox game

Democratizing investing and asset management

Post-apocalyptic sci-fi universe

L1 blockchain with parallel execution

Decentralized Casino

General middle layer

A decentralized savings pool which rewards regular saving

On-chain intent trading protocol


Telegram-based trading and matchmaking platforms

Learn-and-Earn Platform

Payments infrastructure for crypto

Web3 ad network

Starkware-based on-chain gaming ecosystem

Solana NFT gaming project

Modular launch and liquidity solution

Solana-based Crypto AI Incentive Platform

Decentralized insurance platform

Options AMM for crypto assets

Decentralized audio streaming platform

A decentralized talent community

Decentralized Internet Network

High performance underlying blockchain

Bringing BTC, ETH & stablecoins to Algorand

Borrowing and lending platform on Solana

Liquid Staking Protocol on Solana

Margin trading and spot exchange

Decentralized Exchange

SVM-compatible Proof of Work L1

Bitcoin-Native Application Platform

Top-down drone shooter

Decentralized credit scoring protocol

Pixel art NFT metaverse

Concentrated liquidity protocol

A technology company focused on blockchain infrastructure

A system of decentralized finance (DeFi) applications

Isometric play-to-own multiplayer game

Sci-Fi Franchise and Card Game

Multi-chain decentralized keeper network

Decentralized derivatives protocol

Universal risk pricing infrastructure

Layer 1 for Artificial Intelligence

Web3 gaming and NFT analytics platform

Non-bank lenders (NASDAQ: SUIG)

AI-powered Intent Based Infrastructure

Decentralized Exchange

High-performance memory infrastructure

RWAs perpetuals protocol

Filecoin’s premier staking protocol

One-stop DeFi platform

Marketing stack in web3

Web3 AI Infrastructure

Decentralized trading protocol

A web3 gaming metaverse

Multichain DeFi-as-a-Service infrastructure company

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Fantasy Sports World

Decentralized cloud gaming network

Open-world game

Crypto Wallet

NFT Saga MMORPG

Blockchain gaming platform

Oracle network

Self-custody wallet platform and API

Bitcoin boosting network

Identity and social on Arweave

MarketingFi platforms

Multi-agent AI protocol

Intent-based infrastructure & tooling

Luxury watch platform

On-chain reputation & rewards for Web3

Prediction market protocol

Latin American NFT marketplace

Universal cross-chain credit layer

Multiplayer football management game

Fine art marketplace on Solana

Play-to-earn virtual horse racing ecosystem

Decentralized NFT Metaverse with Architecture and Artificial Intelligence

Native Liquidity Structured Protocol

Lightweight wallet
Cyberpunk fighting game

Layer-one blockchain

High-performance layer 1 blockchain

Decentralized blockchain

Layer 1 blockchain

Layer-1 platform

Decentralized enterprise-level GPU cloud network

Penguin NFT Ecosystem

Move-to-Earn app

Network sharing application

The Internet of Blockchains

The Universal Blockchain Settlement Layer

Fully encrypted web3 infrastructure with FHE

Next-gen gaming metaverse

Decentralized protocol for indexing and querying blockchain data

AI Agent Blockchain

Data for AI training

Modular Layer 2 network

Ultra high-performance real-time EVM L2

Decentralized public network

Modular settlement layer

Private blockchain network based on Cosmos SDK

Permissionless Communication Layer on Solana and Bitcoin

Geolocation-based metaverse that converges the virtual and real world

Hardware-accelerated restaking network on Solana

Aggregation infra for DEXs, LSTs and chains

Move-to-earn game

Decentralised network of cameras

Decentralized derivatives exchange

DeFi on Sui starts with Suilend

Financial layer for DeSci

Layer 2 Blockchain Privacy Protocol

Decentralized Data Storage Protocol

The blockchain optimized for gamers

Blockchain and smart transaction platform

Aptos-native DeFi with stablecoin and AMM

DeFi infrastructure backed by RWA

Bridges real world collectibles onto the blockchain

RWA tokenization platform

Bitcoin restaking platform

Decentralized meme token

The decentralized interchangeable assets protocol

OTC platform for the digital asset

NFT lending protocol

Solana's Leading NFT Marketplace

Decentralized trading platform

Universal FHE protocol

Stake pools on the Solana blockchain network

Marketplace for peer-to-peer commerce

Omnichain rollups

Non-custodial peer-to-peer orderbook

Solana 's LSD Protocol

Synthetic Currency Exchange Protocol

Combining RWA and IP platform

Creator platform on the Solana

Solana lending protocol

Parallelized confidential computing network
News
DEXScreener Detects Multiple Paid Token Promotions on Solana
The team at @squire_bot, who is behind UsePod(.)ai and bringing the secondary inference markets to @solana featured on a @Delphi_Digital blogpost Inference Capital Markets are real and VCs are taking notice We will evangelize the market on the power of Clawpump builders https://x.com/shaughnessy11
Solana TPS: theoretical. My actual transaction speed: waiting for the meme to die.
We’re excited to share that @roomsdotrun has been selected for @Alchemy’s $20M Solana ecosystem fund. A few people in a room. An idea. A plan. That’s how real communities start. We’re building launch infrastructure focused on contribution, participation, and long-term alignment on @solana. More
Pudgy Penguins are heading back to San Diego Comic-Con 2026 🐧 We’re proud to return for our fourth year to one of the world’s largest pop culture events and continue our mission of championing Web3 IP. RSVP below.
Thousands of tokens, NFTs, and TCG cards on @solana now have access to a worldwide, permissionless credit desk. Jupiter Offerbook is now in Public Beta, which means you can borrow against anything at a fixed rate and for a fixed term. Offerbook is different from every lending protocol you've ever
RT @_rishinsharma: x402 is not even a year old on @solana . It is obvious that agentic payments has been one of the most exciting areas f…
8.2x up from my call on $flip Join Group 🤑 👉 http://t.me/Memecoin_Gemz CA: HNBHtzGF7NY787hSEf4xnU7GnGbK4fyBP1SMWVxyfLip #memecoin #bbvipks4 https://x.com/Insider_Caller/status/2059657233554653558
JOINING THE SOLANA ECOSYSTEM CALL: @0xSoju Thursday, 28 May. 2PM UTC. Hosted by @SolBrothersPod. Register below. 👇🏻
RT @AvalancheFDN: The Avalanche Foundation is delighted to see @AvaxTeam1 open applications for their latest cohort 🔺 Team1 is a global co…