The top Decentralized Science (DeSci) projects, ranked by prominence — TVL, market cap, funding, and on-chain activity.

BIO Protocol
Decentralized science funding and IP ownership

OriginTrail
Verifiable knowledge infrastructure for decentralized AI

Bluzelle
Decentralized blockchain for science and data.

Silencio
The world's ears for AI and robotics

Factor
The composability engine for DeFi intents.

VitaDAO
Decentralized funding for longevity research

Dynex
Quantum-driven neuromorphic blockchain for real-world problems

The Innovation Game
Open innovation through decentralized algorithm discovery

Galeon
Decentralized AI for sovereign healthcare

yesnoerror
AI research alpha, tokenized on Solana and Base.

Cerebrum DAO
Decentralized funding for brain research breakthroughs

ValleyDAO
Community-owned synthetic biology for climate solutions

D1ckGPT
Your on-chain men's health BioAgent

HairDAO
Network State solving hair loss

Curetopia
DAO focused on eradicating rare diseases

Quantum Biology DAO
The Quantum Biology DAO

CryoDAO

Gridcoin

AthenaDAO
Web3 Women's Health Research DAO

AxonDAO Governance Token

ResearchCoin

Eli5a

AIMX

Cypher Tempre

Data Lake

VitaStem

Aubrai by Bio

DigiHealth

Brain Worms

Rifampicin

Urolithin A

Rejuve.AI

Etica

Senku Ishigami by Virtuals

Isaac X

SOLVE

Deep Worm

HydraDAO

Imprnt

NobleBlocks

PsyDAO

Welshare Health Token

SUI Desci Agents

ZAYA AI

CRYORAT

PoSciDonDAO Token

Knot Diffie-Hellman

SpineDAO Token

HealthSci.AI
