The top DeSci projects, ranked by prominence — TVL, market cap, funding, and on-chain activity.
BIO Protocol
Decentralized science funding and IP ownership
Bluzelle
Decentralized storage for science and AI.
Mira
Decentralized trust layer for AI outputs
VitaDAO
Decentralized funding for longevity research
The Innovation Game
Open innovation through decentralized algorithm discovery
Galeon
Decentralized AI for sovereign healthcare
yesnoerror
AI research alpha, tokenized on Solana and Base.
Cerebrum DAO
Decentralized funding for brain research breakthroughs
Catalyst
Interchain liquidity protocol
PYTHIA
The world's first AI-connected rat.
ValleyDAO
Community-owned synthetic biology for climate solutions
D1ckGPT
Your on-chain men's health BioAgent
Sally A1C
Your AI guide to metabolic health
HairDAO
Network State solving hair loss
Curetopia
DAO focused on eradicating rare diseases
Quantum Biology DAO
The Quantum Biology DAO
NanoVita
Crypto-native DeSci protocol
AthenaDAO
Web3 Women's Health Research DAO
Nema
Biology blockchain platform
ResearchHub
Tokenized Scientific Research Platform
Oncology Network
DeSci Initiative for Cancer Research
LabDAO
An online life science research collective
Space Labs
DeSci Satellite Project
Vibe Bio
New Biotech Companies Using Cryptocurrencies
AminoChain
Tokenizing biology for decentralized R&D
BioFoundry
Decentralized Funding Platform
Descipher
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METANOVA
Decentralized AI drug screening platform
AIvilization
Scientific research projects
Causality Network
DeSci Creator Economy Platfrom
DeBio Network
Decentralization Medical and Bioinformatics Services & Data
dLife
Decentralized human-layer
EpiFun
Decentralized science project
GenesisL1
EVM blockchain for desci applications and DAOs
GRIDNET OS
Decentralized Operating System
Love Health
Healthcare solutions
Mito Systems
Decentralized scientific research platform
OpenSci
DeSci incubation platform
OpSci
Decentralized science organization
origo.fun
An innovative platform based on the Base chain
PeptideDAO
Decentralized health data platform
PlantGang
Decentralized community of citizen scientists
Preprints
Science Tools for Human-AI collaboration
SCI16Z
Decentralized AI-powered paper analysis
Scisets
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Triplicate
Toolkit for scientific discovery
ZayaAI
Digital pathology solution
zygote
NFT projects based on Base
CureX
Desci Meme Coin
SciHub
Community memecoin