The top Made in USA projects, ranked by prominence — TVL, market cap, funding, and on-chain activity.
Uniswap
Decentralized token swapping and governance
Ondo Finance
Institutional-grade finance, onchain and always-on.
Compound
Autonomous lending for open finance.
Orca
The most user-friendly DEX on Solana
dYdX
Decentralized perpetuals exchange on its own chain
Axelar
Secure cross-chain communication for Web3
Jito
First liquid staking with MEV rewards on Solana
Reserve protocol
Create asset-backed currencies for the world
Across Protocol
Optimistic cross-chain bridge with no slippage
Puffer Finance
Building infrastructure for autonomous payments
Blur
The NFT marketplace for pro traders
Ripple
Fast cross-border payments and stablecoin infrastructure
Clearpool
Institutional credit rails for DeFi
Avantis
Largest RWA perps DEX on Base
EigenCloud
Verifiable apps powered by restaked ETH
NEAR Protocol
The blockchain for AI and decentralized agents.
Chainlink
The industry-standard decentralized oracle network
SuperVerse
Unified Web3 ecosystem for gaming, DeFi, and AI
Aerodrome
Base's central liquidity hub and AMM
The Graph
Indexing protocol for open blockchain data
Sei Network
The fastest Layer 1 for parallelized EVM
Wormhole
Secure cross-chain messaging for any blockchain.
Mina
World's lightest blockchain, powered by participants.
Helium
People-powered wireless network for IoT and mobile
Theta Network
Decentralized cloud for AI and entertainment
Casper
Layer-1 blockchain for real-world asset tokenization
Origin Protocol
Multichain yield ecosystem for DeFi users
World Liberty Financial
Earn, borrow, and grow across chains
Altura
Build, scale, and monetize Web3 & AI games
0x
Open-source DEX infrastructure for multi-chain swaps
Pudgy Penguins
The world’s social currency
Jupiter
Lend and borrow crypto on Solana.
Handshake
Decentralized naming for the Internet of Agents
SaucerSwap
Leading decentralized exchange on Hedera
Aleo
Private-by-default blockchain for the web
XION
The truth engine for verifiable AI
io.net
Decentralized GPU network for AI workloads
Layer3
Omnichain identity, incentives, and governance layer
Dexalot
Centralized exchange feel, fully decentralized on-chain.
Arkham
Deanonymizing the blockchain for traders.
Moonwell
Decentralized lending and borrowing on Moonbeam
Pixels
Farm, explore, and own your adventure.
Propy
World's first international real estate marketplace.
Oort
Decentralized cloud for transparent AI
Hivemapper
Decentralized mapping, rewarded with HONEY.
Render
Decentralized GPU compute for rendering and AI
Ankr
Decentralized Web3 infrastructure for all chains
Doodles
Immersive storytelling for a joyful world
Cere Network
First Decentralized Data Cloud for Web3
DigiByte
Secure, fast, decentralized UTXO blockchain