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Top Made in USA Projects

The top Made in USA projects, ranked by prominence — TVL, market cap, funding, and on-chain activity.

Uniswap

Uniswap

Decentralized token swapping for everyone

nearzksyncgnosis+42
$2.5900
-5.50%$1.61B
Ondo Finance

Ondo Finance

Tokenized real-world assets for DeFi yield

ethereumarbitrumstellar+12
Compound

Compound

Algorithmic lending for open finance applications

bnb-chainavalanchenear+10
Orca

Orca

Fast, low-cost AMM on Solana

solanaeclipse
dYdX

dYdX

Leading decentralized derivatives exchange

cosmosdydxethereum+1
Axelar

Axelar

Secure interchain communication for Web3

arbitrumjunokujira+24
Jito

Jito

Liquid staking with MEV rewards on Solana

solana
Reserve protocol

Reserve protocol

Create asset-backed currencies for global purchasing power.

arbitrumbnb-chainethereum+1
Across Protocol

Across Protocol

Instant, capital-efficient cross-chain bridging

polygonarbitrumoptimism+2
Puffer Finance

Puffer Finance

Restaking-driven rollups for Ethereum scalability

bnb-chainethereum
Blur

Blur

The NFT marketplace for pro traders

blastethereum
Ripple

Ripple

Fast, low-cost cross-border payments for institutions.

xrp-ledger
Clearpool

Clearpool

Decentralized credit markets for institutions

optimismpolygon-zkevmbase+7
Avantis

Avantis

Smart perpetuals trading with risk management

base
EigenCloud

EigenCloud

Restake ETH for enhanced cryptoeconomic security

ethereumbase
NEAR Protocol

NEAR Protocol

The scalable Layer 1 for builders

near
Chainlink

Chainlink

The standard for secure blockchain oracles

ethereumfantombase+65
SuperVerse

SuperVerse

Gaming, DeFi, and AI unified

polygonavalanchebase+2
Aerodrome

Aerodrome

Base's prime DEX and liquidity hub.

base
The Graph

The Graph

Decentralized indexing for blockchain data

avalanchenearethereum+3
Sei Network

Sei Network

High-performance Layer 1 for trading

sei
Wormhole

Wormhole

Universal cross-chain messaging protocol.

solanaethereumbase+11
Mina

Mina

The world's lightest blockchain, powered by participants.

Helium

Helium

Decentralized wireless network powered by blockchain

solana
Theta Network

Theta Network

Media and entertainment focused blockchain

theta
Casper

Casper

Layer-1 for real-world asset tokenization

Origin Protocol

Origin Protocol

Multichain DeFi yield ecosystem with staking rewards

ethereumbasesonic
World Liberty Financial

World Liberty Financial

Lend, borrow, and grow your strategy

ethereumsolanabnb-chain
Altura

Altura

Build and monetize Web3 & AI games

basebnb-chainhyperliquid
0x

0x

Open source, decentralized transaction infrastructure

ethereum
Pudgy Penguins

Pudgy Penguins

The token for Pudgy Penguins community and vibes.

ethereumsolanabnb-chain+2
Jupiter

Jupiter

DEX Aggregator

ethereumbnb-chainsolana+1
Handshake

Handshake

Decentralizing the internet's naming system

SaucerSwap

SaucerSwap

Hedera's leading DEX with anti-MEV protection

basehedera
Aleo

Aleo

Platform for private applications

bnb-chain
XION

XION

The first walletless blockchain for mainstream adoption

ethereumbaseosmosis
io.net

io.net

World's largest decentralized computing network for AI

solana
Layer3

Layer3

Omnichain identity, distribution, and incentives

ethereumbnb-chainoptimism+4
Dexalot

Dexalot

Order Book DEX

arbitrumavalanchebnb-chain+3
Arkham

Arkham

Blockchain intelligence Platform

ethereum
Moonwell

Moonwell

Collateralized lending protocol

basemoonrivermoonbeam
Pixels

Pixels

Farm, explore, and own your adventure

ethereumroninton
Propy

Propy

Decentralized real estate for the world

ethereumbase
Oort

Oort

Web3 data infrastructure

ethereumbnb-chain
Hivemapper

Hivemapper

Decentralized mapping, rewarded with HONEY.

solana
Render

Render

Decentralized GPU compute for AI and rendering

ethereumsolana
Ankr

Ankr

avalanchepolygonoptimism+13
Doodles

Doodles

Immersive storytelling for a colorful world

solanabnb-chainethereum
Cere Network

Cere Network

Cloud data infrastructure solutions

ethereumbase
DigiByte

DigiByte

Secure, decentralized blockchain for digital assets and apps