The top Made in USA projects, ranked by prominence — TVL, market cap, funding, and on-chain activity.

Uniswap
Decentralized token swapping for everyone

Ondo Finance
Tokenized real-world assets for DeFi yield

Compound
Algorithmic lending for open finance applications

Orca
Fast, low-cost AMM on Solana

dYdX
Leading decentralized derivatives exchange

Axelar
Secure interchain communication for Web3

Jito
Liquid staking with MEV rewards on Solana

Reserve protocol
Create asset-backed currencies for global purchasing power.

Across Protocol
Instant, capital-efficient cross-chain bridging

Puffer Finance
Restaking-driven rollups for Ethereum scalability

Blur
The NFT marketplace for pro traders

Ripple
Fast, low-cost cross-border payments for institutions.

Clearpool
Decentralized credit markets for institutions

Avantis
Smart perpetuals trading with risk management

EigenCloud
Restake ETH for enhanced cryptoeconomic security

NEAR Protocol
The scalable Layer 1 for builders

Chainlink
The standard for secure blockchain oracles

SuperVerse
Gaming, DeFi, and AI unified

Aerodrome
Base's prime DEX and liquidity hub.

The Graph
Decentralized indexing for blockchain data

Sei Network
High-performance Layer 1 for trading

Wormhole
Universal cross-chain messaging protocol.

Mina
The world's lightest blockchain, powered by participants.

Helium
Decentralized wireless network powered by blockchain

Theta Network
Media and entertainment focused blockchain

Casper
Layer-1 for real-world asset tokenization

Origin Protocol
Multichain DeFi yield ecosystem with staking rewards

World Liberty Financial
Lend, borrow, and grow your strategy

Altura
Build and monetize Web3 & AI games

0x
Open source, decentralized transaction infrastructure

Pudgy Penguins
The token for Pudgy Penguins community and vibes.

Jupiter
DEX Aggregator

Handshake
Decentralizing the internet's naming system

SaucerSwap
Hedera's leading DEX with anti-MEV protection

Aleo
Platform for private applications

XION
The first walletless blockchain for mainstream adoption

io.net
World's largest decentralized computing network for AI

Layer3
Omnichain identity, distribution, and incentives

Dexalot
Order Book DEX

Arkham
Blockchain intelligence Platform

Moonwell
Collateralized lending protocol
Pixels
Farm, explore, and own your adventure

Propy
Decentralized real estate for the world

Oort
Web3 data infrastructure

Hivemapper
Decentralized mapping, rewarded with HONEY.

Render
Decentralized GPU compute for AI and rendering

Ankr

Doodles
Immersive storytelling for a colorful world

Cere Network
Cloud data infrastructure solutions

DigiByte
Secure, decentralized blockchain for digital assets and apps