The top Sequoia Capital Portfolio projects, ranked by prominence — TVL, market cap, funding, and on-chain activity.

Clearpool
Institutional credit rails for DeFi

Magic Eden
The largest NFT marketplace across multiple chains.

DESO
The layer-1 for on-chain social

Handshake
Decentralized naming for the Internet of Agents

Aergo
Flexible blockchain platform for enterprise dApps

STEPN
Move to earn with NFT sneakers

Hooked Protocol
Gamified on-ramp for Web3 adoption

Filecoin
Decentralized storage marketplace for the world

Orchid Protocol
Peer-to-peer bandwidth marketplace for private internet access.

Conflux
Regulatory-compliant layer 1 bridging East and West

ARAI
AI companions and tokenized pets for Web3 gaming

Orderly Network
Permissionless liquidity layer for Web3 trading

Multichain
defunctDecentralized cross-chain router for Web3

pSTAKE Finance
Liquid staking and yield for Bitcoin

Nervos Network
Layered trust network for crypto-economy

LayerZero
The universal cross-chain messaging layer

IOST

FTX
defunctCentralized exchange for crypto derivatives and tokenized assets

Band

Iron Fish

Huobi

Pulsr
NFT discovery engine

Index Cooperative

Arena-Z

Multichain (BSC)

Beta Finance

League of Kingdoms

StarkNet
decentralized ZK-Rollup