The top Synthetic Issuer projects, ranked by prominence — TVL, market cap, funding, and on-chain activity.
Synthetix
Permissionless derivatives liquidity protocol
arbitrumavalanchebase+7
Metronome
First autonomous cross-chain cryptocurrency
baseethereumoptimism
Metronome
First autonomous cross-chain cryptocurrency
baseethereumoptimism
AWE Network
Autonomous worlds for AI agent collaboration at scale
baseethereum
Horizon Protocol
Trade synthetic assets with deep liquidity and leverage
bnb-chain
Horizon Protocol
Trade synthetic assets with deep liquidity and leverage
bnb-chain
DAFI Protocol
Trade Without Limits on the Hybrid Exchange
bnb-chainethereumpolygon
DAFI Protocol
Trade Without Limits on the Hybrid Exchange
bnb-chainethereumpolygon
UMA
Optimistic-based oracle
arbitrumavalancheethereum
Mettalex
Decentralized commodities derivatives trading platform
ethereum
Cryptex Finance
Ethereum-based DeFi protocol
baseethereum
Indigo Protocol
cardano
Offshift
Private Derivatives Platform
bnb-chainethereum
Mirror Protocol
bnb-chainethereumterra-classic
Jarvis
arbitrumbasebnb-chain+4
Jarvis Reward
arbitrumavalanchebnb-chain+3
Selenium
terra-classic